FRESH-PEF60112-en
Study of genetic factors implied into autism and related disorders
AUTISME
| Name | Country code |
|---|---|
| France | fr |
['Clinical data','Participant-reported health data','Biological data','Paraclinical data (non-biological) : Imaging']
Individuals
| Topic | Vocabulary |
|---|---|
| Neurology | health theme |
| Psychiatry | health theme |
| Autism spectrum disorder | cim-11 |
| Biological determinants: Genetic predisposition | health determinant |
| Biological determinants | health determinant |
{
"level_sex_clusion_I": [
{
"value": "Female",
"concept": {
"vocab": "MeSH",
"vocabURI": "http:\/\/id.nlm.nih.gov\/mesh\/D005260"
}
}
],
"level_age_clusion_I": [
{
"value": "Child (6 to 12 years)",
"concept": {
"vocab": "MeSH",
"vocabURI": "http:\/\/id.nlm.nih.gov\/mesh\/D002648"
}
}
],
"level_type_clusion_I": [
"Patients population"
],
"level_type_clusion_other": "",
"clusion_I": "Of patients or subjects called proposers : - patient with autism, filling DSM-IV (American Psychiatric Association, 1994) diagnostic criteria, and ADI-R (Autism Diagnostic interview-revised, Lord et Coll., 1994) for autism Or Patient with Asperger syndrome, filling DM-IV criteria, as well as ASDI (Asperger Syndrome Diagnostic Interview, Gillberg et Coll., 2001) for Asperger syndrome Or Patient with TSA-NS filling DSM-IV diagnostic criteria; - At least 2 years old, with no further age limit ; - Somatic condition compatible with a blood sample; - Social security scheme membership - Informed consent signature. Of first degree relatives (parents, brothers and sisters): - Informed consent signature - Somatic and intellectual condition compatible with a blood sample - Social security scheme membership Of adult controls: - Aged between 18 and 50; - Being Caucasian; - Absence of psychiatric pathology, verified with DIGS (Diagnostic Interview for Genetic Studies, Nurnberger et coll., 1994) for adults; - Somatic and intellectual condition compatible with a blood sample - Informed consent signature - Social security scheme membership Of child controls: - At least 2 years old, with no further age limit; - Being Caucasian; - Beneficiary of social security scheme; - Absence of psychiatric pathology verified with Kiddie-sads (kiddie schedule for affective disorders and schizophrenia for school-age children, Orvaschel et Coll., 1982); - Parents or legal guardians informed consent signature",
"clusion_E": ""
}
| Name |
|---|
| Marion;LEBOYER |
| Thomas;BOURGERON |
| Name | Role |
|---|---|
| INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) | sponsor |
| Name |
|---|
| ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP) |
| FONDATION D ENTREPRISE ORANGE |
| Fondation FondaMental |
| INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
['Through organizations (health services or institutions, schools, businesses, etc.)']
['{"concept":{"vocabURI":"Other","vocab":"CESSDA"},"value":"Other"}']
Access on specific project only
Observational Study
| Start | End |
|---|---|
| 1995-01-01 | 3000-01-01 |
['Coherence request during after computer data entry; Missing data management; Doctors remainders for follow-up visits; Patients receive written information about the use of their data.']
Access condition : international USA collaboration (Autism Genome Project) leading to publications.
{"value":"Restricted access","extLink":[{"title":"COAR","uri":"http://purl.org/coar/access_right/c_16ec"}]}
Possible data utilization by academic teams. Data exploitation not available for industry sectors.
| Name | |
|---|---|
| Marion;LEBOYER | marion.leboyer@inserm.fr |
| Thomas;BOURGERON | thomas.bourgeron@pasteur.fr |
FRESH-PEF60112-en
| Name | Affiliation |
|---|---|
| Marion LEBOYER | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |