FRESH-PEF60115-en
Asthma and Airway Obstruction Cohort: Clinicobiological Cohort Follow-up
COBRA
| Name | Country code |
|---|---|
| France | fr |
['Clinical data','Participant-reported health data','Biological data','Paraclinical data (non-biological) : Imaging']
Individuals
| Topic | Vocabulary |
|---|---|
| Pulmonary medicine | health theme |
| Environmental determinants: Climate | health determinant |
| Environmental determinants | health determinant |
{
"level_sex_clusion_I": [
{
"value": "Male",
"concept": {
"vocab": "MeSH",
"vocabURI": "http:\/\/id.nlm.nih.gov\/mesh\/D008297"
}
},
{
"value": "Female",
"concept": {
"vocab": "MeSH",
"vocabURI": "http:\/\/id.nlm.nih.gov\/mesh\/D005260"
}
}
],
"level_age_clusion_I": [
{
"value": "Young Adult (19 to 24 years)",
"concept": {
"vocab": "MeSH",
"vocabURI": "http:\/\/id.nlm.nih.gov\/mesh\/D055815"
}
},
{
"value": "Adult (25 to 44 years)",
"concept": {
"vocab": "MeSH",
"vocabURI": "http:\/\/id.nlm.nih.gov\/mesh\/D000328"
}
},
{
"value": "Middle Aged (45 to 64 years)",
"concept": {
"vocab": "MeSH",
"vocabURI": "http:\/\/id.nlm.nih.gov\/mesh\/D008875"
}
},
{
"value": "Aged (65 to 79 years)",
"concept": {
"vocab": "MeSH",
"vocabURI": "http:\/\/id.nlm.nih.gov\/mesh\/D000368"
}
}
],
"level_type_clusion_I": [
"Patients population"
],
"level_type_clusion_other": "",
"clusion_I": "Two cohorts: one with asthmatics and one with individuals affected by COBP; subjects included between the ages of 18 and 80 years old. Asthma cohort: including patients who are non-smokers and smokers with compatible clinical history and individuals with a reversible obstructive airway disease, based on a FEV1\/CV <75% and an FEV1 baseline value improvement of 12% or 200 ml after inhalation of 400 µg of Salbutamol. COBP cohort: including patients who are smokers (>10 packets per year) presenting with an obstructive airway disease (FEV1\/CV <75%) and an FEV1 improvement of less than 10% after inhalation of 200 µg of Salbutamol.",
"clusion_E": ""
}
| Name |
|---|
| Michel;AUBIER |
| Name | Role |
|---|---|
| INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) | sponsor |
| Name |
|---|
| ASTRAZENECA (FRANCE) |
| CENTRE HOSPITALIER UNIVERSITAIRE DE NIMES (CHU) |
| CHIESI (FRANCE) |
| GLAXOSMITHKLINE (FRANCE) |
| INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
['Through organizations (health services or institutions, schools, businesses, etc.)']
['{"concept":{"vocabURI":"Other","vocab":"CESSDA"},"value":"Other"}']
Access on specific project only
Observational Study
| Start | End |
|---|---|
| 2008-01-01 | 2018-01-01 |
Contractual access subject to COBRA Scientific Council validation. Research projects that can use clinical and/or biological cohort data are encouraged and validated by the Scientific Council (2 members per centre).
{"value":"Restricted access","extLink":[{"title":"COAR","uri":"http://purl.org/coar/access_right/c_16ec"}]}
Data may be used by academic teams. Data may not be used by industrial teams.
| Name | |
|---|---|
| Michel;AUBIER | michel.aubier@wanadoo.fr |
FRESH-PEF60115-en
| Name | Affiliation |
|---|---|
| Michel AUBIER | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |